I got a Raspberry pi 3b with PiHole on it and was able to give it a second IP-Address and i did bind the lighttpd server from PiHole to one IP and I installed a Node-Red Server and did bind it to the second IP.
Now when i reboot the Pi lighttpd wont start, but if i log in over ssh and start lighttpd manually it starts without any issues. I start it with the command sudo systemctl start lighttpd. The log file /var/log/lighttpd/error.log is empty and the log file /var/log/lighttpd/error-pihole.log only says that the server was stopped at reboot but not started.